Karyne N. Rabey

My primary research interests are found in areas that include both the mechanics of locomotion and human musculoskeletal health. I am particularly interested in understanding how certain life history variables influence muscle-bone interactions. Specifically, my postdoctoral research looks at the effects of aging (early and late phases), sex, nutrition, exercise, vibration and pregnancy on musculoskeletal health. I have been working with Daniel Schmitt to document the effects of these variables on bone and muscle strength and have been asking if changes in those properties influence gait mechanics. I am also collaborating with Farshid Guilak (Duke) and Mark Hamrick (Georgia Regents University) to look at these factors on osteoporosis, osteoarthritis, and sarcopenia.

Before coming to Duke, I was at the University of Toronto looking at the muscle attachments of the forelimbs in primates and mice. My doctoral research tested the hypothesis that activity and muscle architecture influences muscle attachment morphology, with the goals of improving our abilities to understand the development and maintenance of attachment sites, and to reconstruct the behavioural and health patterns of past populations. This project allowed me to collaborate with David Begun (University of Toronto), David Green (Midwestern University), ShannonMcFarlin (George Washington University), Brian Richmond (AMNH), and AndreaTaylor (Duke).

This year I had the privilege of joining a non-profit organization called Medical Students for Haiti to teach a case-based course in human gross and clinical anatomy at the Universit√© Quisqueya in Port-au-Prince, Haiti. I plan on continuing being involved with the course and Dr. Genevi√®ve Poitevien in the years to come.


Rabey KN, Green DJ, Taylor AB, Begun DR, Richmond BG, McFarlin SC. 2014. Locomotor activity influences muscle architecture and bone growth but not muscle attachment site morphology. Journal of Human Evolution (In Press) [PDF].

McNeill J, Wu C-L, Rabey KN, Schmitt D, Guilak F. 2014. Life-long caloric restriction does
not alter the severity of age-related osteoarthritis. Age. 36 (4): 9669. [PDF]

Associated Links:
Hard Tissue Research Laboratory CASHP